05.2021.18.32

Synthesis, Characterization and Optimization of New Silicone Hydrogel Contact Lens Materials prepared by Free Radical Photopolymerization

Author(s):

Dhuha Jawad Hussein, Ruaa jameel kamel, Farah Safi Khliwi‡†, Mohammed Ali Mutar‡‡

Affiliation(s):

Chemical Engineering Department, College of Engineering, Al-Qadisiyah University, Al Diwaniyah, Qadisiyyah Province, Iraq.

College of pharmacy Al-Qadisiyah University, Al Diwaniyah, Qadisiyyah Province, Iraq.

‡†Department of Chemistry, College of Education, Al-Qadisiyah University, Al Diwaniyah, Qadisiyyah Province, Iraq.

‡‡Department of Enviermental, College of Science, Al-Qadisiyah University, Al Diwaniyah, Qadisiyyah Province, Iraq.

Corresponding Author Email: duha.jawad9045@gmail.com

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Silicone hydrogel contact lenses (SiHy) are modern and advanced lenses with distinctive properties compared to other lenses; The basis of their design is to have high oxygen permeability. In this paper, silicone-based contact hydrogel lenses were fabricated by polymerizing 3- (methacryloxypropyl TRIS (trimethylsiloxy) silane (TRIS) with N, 1-vinyl 2- pyrrolidone (NVP), Methacrylate (MA), 2-hydroxyethyl methacrylate, and 2-Hydroxyethyl acrylate (HEMA). A feature for silicone hydrogel lenses has been studied through several laboratory tests to ensure the validity of these lenses, including equilibrium water content, oxygen permeability, mechanical properties, optical transparency, protein absorption, contact angle, and bacterial attachment. The outcomesshowed which the TRIS component in each component raised oxygen permeability as well as reduced the equilibrium water component, whilst (NVP& HEMA) -co-TRIS and increased equilibrium water content (EWC)%. The highest oxygen penetration value was 140barrers, corresponding to a 86%equilibriumwater content. Overall, the silicon hydrogels in this work showed adequate oxygen permeability as well as optical transparency and anti-protein absorption. Therefore, polymers made of silicone hydrogel may have the potential to be among the polymers made of contact lenses.