Fabrication of Zinc calcium phosphate for antibacterial applications


Roaa Saad, Shaker J. Edrees, Aseel Hadi


Department of Ceramics Engineering and Building Materials, Faculty of Materials Engineering, University of Babylon, Babylon, Iraq.

Corresponding Author Email: stud.roaa.saad@uobabylon.edu.iq, mat.shaker.jahil@uobabylon.edu.iq, mat.Aseel.hadi.@uobabylon.edu.iq, aseel16484@yahoo.com

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Zinc calcium phosphate is one of the important biological and antibacterial materials. The major objective of this research is estimating the possibility of forming zinc calcium phosphate [Ca19Zn2(PO4)14] by substituted Ca2+ by Zn2+ in the hydroxyapatite structure. In this study was prepared pure hydroxyapatite and zinc calcium phosphate at percent of zinc (0, 8) mol% ZnO by Sol-Gel technique. The resultant powders was sintering at 1100º C. The precursor materials are calcium nitride, di-ammonium hydrogen phosphate, zinc nitride, and ammonium hydroxide solution. At 8 mol% of ZnO, zinc calcium phosphate was successfully obtained. Testing the morphological properties was done by using Transmission electron microscopy (TEM), Field Emission- Scanning Electron Microscopy (FE-SEM), and Energy Dispersive X-Ray Spectroscopy (EDS). TEM results found the particles like rode with nano size. FE-SEM results tested after sintering at 1100ºC found that the particles agglomerated more when adding 8mol% ZnO. For testing the bioactivity was done by immersion the compacted the samples in simulated body fluid (SBF). XRD and FE-SEM tests shown that appetite layers formed on the samples surface, giving an evidence of their bioactivity. The antibacterial activity tested against Escherichia coli. Generally, adding zinc to the hydroxyapatite resulted the smaller particle size obtained, that mean high surface area of bioceramic powder, and subsequently improve the bone bonding ability and improve the bioactivity compared with pure hydroxyapatite.